back of the fridge
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#storage-coldchain 2025-06-09
Monday39 messages8 participantstimes are UTC
Highlights from this day
- coa_or_cope — right so what temperature does a domestic fridge door actually swing to 20:01
- coa_or_cope — i have never had a lyophilised vial fail after a warm transit and i have had some bad ones, ymmv 20:18
- appetite_back — do you keep the unopened vials and the in-use one in the same place 21:01
- fridge_thermo — reconstituted solution is the fragile part. that is where the cold chain actually earns its keep, not advice obviously 21:04
- cold_chain_cmdr — genuine question hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 21:45
does anyone freeze reconstituted vials or is that madness
how cold is too cold, can it actually freeze in a normal fridge
freezing reconstituted peptide is the one thing this channel has never agreed on
two to eight degrees. most domestic fridge doors are not in that range and people do not check
hand luggage
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
does the fridge in a hotel room count as a fridge
*VendorInvestigate not the other one
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
how do you keep it cold on a long drive in summer
i log the fridge temperature daily and the room has never let me forget it
anyone tested a vial before and after a bad transit
for flying, hand luggage every time. the hold is not temperature controlled the way people assume, i could be wrong
buy a thermometer
if you are worried after a bad transit, test it. that is what the testing channels are for
not the door
a liquid cold pack tells you it was above freezing, not that your vial cooked
[edited]flying with vials, hand luggage or checked
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log it
a cooler with two gel packs held under eight degrees for eleven hours on a drive
i keep everything at the back of the middle shelf, never the door, someone check my working
i would use it
lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear, we shall see
right so what temperature does a domestic fridge door actually swing to
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solution is not
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones, ymmv
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i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
how long is reconstituted actually good for at room temperature
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back
test it
do you keep the unopened vials and the in-use one in the same place
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freeze debate again
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep, not advice obviously
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
my fridge is 4.8
genuine question hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct