quick one power cut for 9 hours, fridge stayed shut, am i fine
#storage-coldchain 2025-08-01
Friday30 messages8 participantstimes are UTC
Highlights from this day
- quiet_head_qi — hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 12:34
- mira_pins — follow up the vial that visibly changed after a warm transit was the one that had already been reconstituted 13:53
- quiet_head_qi — the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in 14:01
- quiet_head_qi — quick one i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why 14:55
- gip_glp_gil — does anyone freeze reconstituted vials or is that madness 16:04
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
do i need to worry about light exposure or is that overthinking
i left it out overnight by accident, bin it or use it
if you are worried after a bad transit, test it. that is what the testing channels are for, ymmv
anyone tested a vial before and after a bad transit
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
thats fine
🔥15✅11
log it
👀3🧊15
follow up the vial that visibly changed after a warm transit was the one that had already been reconstituted
two to eight
door shelf or back of the fridge
how long is reconstituted actually good for at room temperature
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
🙏2
do you keep the unopened vials and the in-use one in the same place
i keep everything at the back of the middle shelf, never the door
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
update from 8 months ago: replaced the fridge, temperature is stable, no more anxiety
quick one i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
my fridge is running at 7.4, is that out of range
a cooler with two gel packs held under eight degrees for eleven hours on a drive
is a five pound fridge thermometer actually worth it
*VendorInvestigate not the other one
does anyone freeze reconstituted vials or is that madness
🧊4❤️1
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
*that should say weekly
lyophilised at room temp for 26 days in transit, worried or not
i log the fridge temperature daily and the room has never let me forget it