update on the earlier thing i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
#storage-coldchain 2025-09-02
- vik_verifies — update on the earlier thing i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine 18:48
- vik_verifies — i log the fridge temperature daily and the room has never let me forget it for flying, hand luggage every time. the hold is not temperature controlled the way people… 19:19
- vik_verifies — nobody here can tell you a vial is safe. we can tell you what has and has not survived for us 20:31
- otto_swirls — buy a thermometer. mine reads 4 on the door and two degrees lower at the back 21:55
if you are worried after a bad transit, test it. that is what the testing channels are for, ymmv
buy a thermometer
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
gel packs
i log the fridge temperature daily and the room has never let me forget it
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
light exposure matters much less than temperature for these. i still keep them in the carton
solution is not
hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct, someone check my working
flying with vials, hand luggage or checked
update from 1 months ago: replaced the fridge, temperature is stable, no more anxiety
coming back after 14 months, is the pinned storage table still current
i would use it
power cut for 3 hours, fridge stayed shut, am i fine
freezing reconstituted peptide is the one thing this channel has never agreed on
while im here does the amber vial thing matter or is it marketing
does the fridge in a hotel room count as a fridge
[edited]freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
update from 15 months ago: replaced the fridge, temperature is stable, no more anxiety
freeze debate again
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well, i could be wrong
[edited]genuine question the vial that visibly changed after a warm transit was the one that had already been reconstituted
a liquid cold pack tells you it was above freezing, not that your vial cooked
do you log the fridge temperature or is that too far
does anyone freeze reconstituted vials or is that madness
a cooler with two gel packs held under eight degrees for eleven hours on a drive
do you keep the unopened vials and the in-use one in the same place
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
log it
my fridge is 3.1
i keep everything at the back of the middle shelf, never the door
hand luggage
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
buy a thermometer. mine reads 4 on the door and two degrees lower at the back
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in, thats just me
a few hours at room temperature is almost certainly nothing. a week is a different conversation