i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
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#storage-coldchain 2025-10-10
Friday20 messages5 participantstimes are UTC
Highlights from this day
- deamidation — i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why the practical risk in winter shipping is freezing, and in… 19:48
- two_four_ceiling — power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well 20:01
- two_four_ceiling — if you are worried after a bad transit, test it. that is what the testing channels are for 20:13
- mg_per_ml — update on the earlier thing i log the fridge temperature daily and the room has never let me forget it 20:48
- marrow.mod — lyophilised at room temp for 17 days in transit, worried or not 21:58
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well
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coming back to this a liquid cold pack tells you it was above freezing, not that your vial cooked, for what its worth
if you are worried after a bad transit, test it. that is what the testing channels are for
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follow up coming back after 10 months, is the pinned storage table still current
my fridge is running at 6.2, is that out of range
is there a difference in stability between the compounds
i have never had a lyophilised vial fail after a warm transit and i have had some bad ones, happy to be corrected
not the freezer
the vial that visibly changed after a warm transit was the one that had already been reconstituted
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update on the earlier thing i log the fridge temperature daily and the room has never let me forget it
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flying with vials, hand luggage or checked
buy a thermometer. mine reads 3.1 on the door and two degrees lower at the back, someone check my working
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
buy a thermometer
the door swings four or five degrees every time somebody opens it. the back barely moves
lyophilised at room temp for 17 days in transit, worried or not
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8genuine question i keep everything at the back of the middle shelf, never the door, i think
*PeptideMeter not the other one
power cut for 7 hours, fridge stayed shut, am i fine
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it