if you are worried after a bad transit, test it. that is what the testing channels are for
#storage-coldchain 2025-12-14
Sunday33 messages8 participantstimes are UTC
Highlights from this day
- lean_mass_lex — a cooler with two gel packs held under eight degrees for eleven hours on a drive 16:35
- birch_bloods — flying with vials, hand luggage or checked 18:01
- apnoea_down_two — update from 3 months ago: replaced the fridge, temperature is stable, no more anxiety reconstituted solution is the fragile part. that is where the cold chain… 18:50
- ten_of_ten — i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why 20:53
- ten_of_ten — do you log the fridge temperature or is that too far 21:32
a cooler with two gel packs held under eight degrees for eleven hours on a drive
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is there a difference in stability between the compounds
how long is reconstituted actually good for at room temperature
not the freezer
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8freeze debate again
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lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
door shelf or back of the fridge
the door swings four or five degrees every time somebody opens it. the back barely moves
if you are worried after a bad transit, test it. that is what the testing channels are for
freezing reconstituted peptide is the one thing this channel has never agreed on
flying with vials, hand luggage or checked
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hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
lyophilised at room temp for 22 days in transit, worried or not
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
update from 3 months ago: replaced the fridge, temperature is stable, no more anxiety
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
i would use it
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
[edited]i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
i would bin it
how do you keep it cold on a long drive in summer
ok so does the fridge in a hotel room count as a fridge
swab_dry_firstnobody here can tell you a vial is safe. we can tell you what has and has not survived…
does anyone freeze reconstituted vials or is that madness
ok so i have never had a lyophilised vial fail after a warm transit and i have had some bad ones, for what its worth
buy a thermometer. mine reads 6.2 on the door and two degrees lower at the back
[edited]two to eight degrees. most domestic fridge doors are not in that range and people do not check, take that with a pinch of salt
for flying, hand luggage every time. the hold is not temperature controlled the way people assume
back of the fridge
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well, still working it out
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why
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two to eight
do you log the fridge temperature or is that too far
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