i keep everything at the back of the middle shelf, never the door
#storage-coldchain 2026-02-07
Saturday31 messages9 participantstimes are UTC
Highlights from this day
- pinch_not_stretch — light exposure matters much less than temperature for these. i still keep them in the carton 22:21
- VialBot — Reminder for ferritin_fay: dose day is today. Set 4 days ago. 22:34
- sasha_stacks — for the archive two to eight degrees. most domestic fridge doors are not in that range and people do not check 23:29
update on the earlier thing freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
update on the earlier thing nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
two to eight
gel packs
i would use it
light exposure matters much less than temperature for these. i still keep them in the carton
| Condition | Lyophilised | Reconstituted |
|---|---|---|
| 2-8 °C | fine, long term | fine, weeks |
| Room temp, days | fine in every report here | reported fine, shorter |
| Room temp, weeks | reported fine | do not |
| Warm transit, 30 °C+ | no failure logged | one visible degradant peak |
| Frozen once | fine | contested, no consensus |
| Freeze-thaw cycled | fine | the room says no |
update on the earlier thing for flying, hand luggage every time. the hold is not temperature controlled the way people assume
i log the fridge temperature daily and the room has never let me forget it
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my fridge is 4.8
do i need to worry about light exposure or is that overthinking
Reminder for ferritin_fay: dose day is today. Set 4 days ago.
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update from 5 months ago: replaced the fridge, temperature is stable, no more anxiety
freeze debate again
log it
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hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why, happy to be corrected
i would bin it
the door swings four or five degrees every time somebody opens it. the back barely moves
i left it out overnight by accident, bin it or use it
buy a thermometer. mine reads 4 on the door and two degrees lower at the back
a liquid cold pack tells you it was above freezing, not that your vial cooked, happy to be corrected
a few hours at room temperature is almost certainly nothing. a week is a different conversation, anyway
coming back after 23 months, is the pinned storage table still current
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if you are worried after a bad transit, test it. that is what the testing channels are for, your mileage will differ
not the freezer
a cooler with two gel packs held under eight degrees for eleven hours on a drive
for the archive two to eight degrees. most domestic fridge doors are not in that range and people do not check
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
power cut with the door shut for a few hours is fine. a full fridge holds temperature surprisingly well