vialroom

#storage-coldchain 2026-02-19

Thursday43 messages11 participantstimes are UTC
Highlights from this day
  • tallinn_taper — quick one how do you keep it cold on a long drive in summer 19:06
  • tallinn_taper — a cooler with two gel packs held under eight degrees for eleven hours on a drive 19:13
  • declared_value — i keep everything at the back of the middle shelf, never the door 19:15
  • wren_weighs_in — does the amber vial thing matter or is it marketing 21:21
  • VialBot — Archive lookup: rotate_the_site first appears in this channel on 2025-11-06. 21:38
SS

i log the fridge temperature daily and the room has never let me forget it

SS

if you are worried after a bad transit, test it. that is what the testing channels are for

weights-monthly.csv
399 rows · not retained in the public archive
TT

quick one how do you keep it cold on a long drive in summer

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TT

a cooler with two gel packs held under eight degrees for eleven hours on a drive

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DV

i keep everything at the back of the middle shelf, never the door

ConditionLyophilisedReconstituted
2-8 °Cfine, long termfine, weeks
Room temp, daysfine in every report herereported fine, shorter
Room temp, weeksreported finedo not
Warm transit, 30 °C+no failure loggedone visible degradant peak
Frozen oncefinecontested, no consensus
Freeze-thaw cycledfinethe room says no
TT

i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why

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TT

i have never had a lyophilised vial fail after a warm transit and i have had some bad ones

buy a thermometer. mine reads 4 on the door and two degrees lower at the back

what temperature does a domestic fridge door actually swing to

LL

reconstituted solution is the fragile part. that is where the cold chain actually earns its keep, from memory

nobody here can tell you a vial is safe. we can tell you what has and has not survived for us

a liquid cold pack tells you it was above freezing, not that your vial cooked

PP

do you keep the unopened vials and the in-use one in the same place

do you log the fridge temperature or is that too far

LL

the vial that visibly changed after a warm transit was the one that had already been reconstituted

NP

hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct, your mileage will differ

hand luggage

VB

On this day 3 years ago this channel logged 25 messages.

NP

update from 21 months ago: replaced the fridge, temperature is stable, no more anxiety

👀2

freezing reconstituted peptide is the one thing this channel has never agreed on

two to eight

PM

lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear

WW

the door swings four or five degrees every time somebody opens it. the back barely moves

WW

for flying, hand luggage every time. the hold is not temperature controlled the way people assume, for what its worth

SS

the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in

a few hours at room temperature is almost certainly nothing. a week is a different conversation

fridge-thermometer.png
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test it

gel packs

i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine

NP

thats fine

mon  4.1 / door 7.2
tue  4.0 / door 7.8
wed  4.2 / door 6.9
thu  3.9 / door 7.4
fri  4.1 / door 8.1   <- shopping day
sat  4.3 / door 7.0
sun  4.0 / door 6.8
VB

Archive lookup: rotate_the_site first appears in this channel on 2025-11-06.

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RT

unopened and in-use in the same place is fine. just keep the in-use one where you can reach it

while im here two to eight degrees. most domestic fridge doors are not in that range and people do not check