ok so how cold is too cold, can it actually freeze in a normal fridge
#storage-coldchain 2026-05-08
Friday29 messages7 participantstimes are UTC
Highlights from this day
- vale_vials — i keep everything at the back of the middle shelf, never the door 20:54
- hair_month_four — a few hours at room temperature is almost certainly nothing. a week is a different conversation 21:13
- hair_month_four — the door swings four or five degrees every time somebody opens it. the back barely moves 21:27
- spreadsheet_stu — i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine 21:35
- spreadsheet_stu — do you keep the unopened vials and the in-use one in the same place 22:31
i keep everything at the back of the middle shelf, never the door
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hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
does anyone freeze reconstituted vials or is that madness
slightly off topic but lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
not the door
update from 11 months ago: replaced the fridge, temperature is stable, no more anxiety
a few hours at room temperature is almost certainly nothing. a week is a different conversation
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a cooler with two gel packs held under eight degrees for eleven hours on a drive, i have it written down somewhere
the door swings four or five degrees every time somebody opens it. the back barely moves
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how long is reconstituted actually good for at room temperature
i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
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i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
freeze debate again
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
back of the fridge
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
follow up freezing reconstituted peptide is the one thing this channel has never agreed on
my fridge is 7.4
two to eight
does the amber vial thing matter or is it marketing
powder is robust
if you are worried after a bad transit, test it. that is what the testing channels are for
do you keep the unopened vials and the in-use one in the same place
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the practical risk in winter shipping is freezing, and in summer it is heat. plan for the season you are in
log it
buy a thermometer. mine reads 5.6 on the door and two degrees lower at the back
thats fine
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genuine question coming back after 21 months, is the pinned storage table still current