lyophilised powder is genuinely robust. a warm transit is far less likely to matter than people fear
two to eight degrees. most domestic fridge doors are not in that range and people do not check
#storage-coldchain 2026-06-28
Sunday31 messages8 participantstimes are UTC
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- swirl_not_shake — ok so power cut for 2 hours, fridge stayed shut, am i fine 08:07
- swirl_not_shake — freeze thaw cycling is the risk, not one freeze. that is my read of it anyway, we shall see 08:12
- cold_start_cy — genuine question hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct 08:29
i freeze aliquots and have had them test fine afterwards. others here would not do it and i understand why, n of 1 obviously
is a five pound fridge thermometer actually worth it
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anyone tested a vial before and after a bad transit
i would use it
buy a thermometer. mine reads 4.8 on the door and two degrees lower at the back, take that with a pinch of salt
a cooler with two gel packs held under eight degrees for eleven hours on a drive, for what its worth
does anyone freeze reconstituted vials or is that madness
follow up nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
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test it
i keep everything at the back of the middle shelf, never the door
two to eight degrees. most domestic fridge doors are not in that range and people do not check
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it, still working it out
freezing reconstituted peptide is the one thing this channel has never agreed on, n of 1 obviously
the door swings four or five degrees every time somebody opens it. the back barely moves
two to eight
ok so power cut for 2 hours, fridge stayed shut, am i fine
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i left a reconstituted vial out overnight once, sent it for testing out of curiosity, it came back fine
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a few hours at room temperature is almost certainly nothing. a week is a different conversation, ymmv
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i have never had a lyophilised vial fail after a warm transit and i have had some bad ones
freeze thaw cycling is the risk, not one freeze. that is my read of it anyway, we shall see
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8😂13🧊17
i log the fridge temperature daily and the room has never let me forget it
nobody here can tell you a vial is safe. we can tell you what has and has not survived for us
unrelated but flying with vials, hand luggage or checked
genuine question hotel minibars are frequently not cold enough. i take a thermometer, which is ridiculous and also correct
mon 4.1 / door 7.2
tue 4.0 / door 7.8
wed 4.2 / door 6.9
thu 3.9 / door 7.4
fri 4.1 / door 8.1 <- shopping day
sat 4.3 / door 7.0
sun 4.0 / door 6.8New independent result logged — ERP, lot B-0114, purity 98.6% (Medutest).
how cold is too cold, can it actually freeze in a normal fridge
coming back to this not the freezer
back of the fridge
thats fine
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
11:49marrow.mod pinned a message to this channel