freeze thaw cycling is the risk, not one freeze. that is my read of it anyway
Thread · #storage-coldchain · 2025-04-16
anyone had a vial visibly change after a warm
Spun off from a message in #storage-coldchain on 2025-04-16. 10 messages, 4 participants.
The message this came from
- two_three_lifts — anyone had a vial visibly change after a warm transit 13:05
not the freezer
📈17❤️18
log it
unopened and in-use in the same place is fine. just keep the in-use one where you can reach it
⚠️5🎉2
best travel setup for 21 days away with vials
a few hours at room temperature is almost certainly nothing. a week is a different conversation
🤝10
powder is robust
reconstituted solution is the fragile part. that is where the cold chain actually earns its keep
i left it out overnight by accident, bin it or use it
a cooler with two gel packs held under eight degrees for eleven hours on a drive