unrelated but my read after three years of this: purity is mostly fine across the market and fill consistency is where suppliers differ
#test-results 2025-03-16
Sunday31 messages6 participantstimes are UTC
Highlights from this day
- reta_low_dose — weigh the vial before you reconstitute. it costs nothing and catches the common failure 16:15
- reta_low_dose — follow up what interests me is when the gap goes the same direction every time. once is noise, three times is a pattern 16:29
- stack_sceptic — if you are testing to settle an argument you will not settle it with n of 1 17:20
*VendorInvestigate not the other one
sorry to jump in do you test every order or sample it
fridge-temps.csv
431 rows · not retained in the public archive
99.2 against a certificate of 98.1 is fine. the same supplier landing low four times in a row is a question
one bad test does not condemn a supplier. one good test does not clear one. both halves get ignored equally
thats not great
test it again
which lab
| Evidence | Counts? |
|---|---|
| Independent report, lot you bought, lot number legible | yes |
| Independent report, no lot number | no |
| Supplier certificate only | no |
| Screenshot of a report | no |
| Blinded pooled submission | yes, for the pool |
| A friend who said it was fine | no |
thats within range
while im here does anyone log the negative results, the boring ones
❤️4
log the boring ones
*PeptideMeter not the other one
quick one i have never regretted spending the money on a test. i have regretted not testing twice
certificate said 99.2 and the independent came back 99.4, is that a problem
the widest spread in my data is about 2.6 percentage points across five lots from one supplier
transit-times.csv
438 rows · not retained in the public archive
log the lot number
📉1📈1🔥12
does a bad result on one lot condemn the whole supplier
weigh the vial before you reconstitute. it costs nothing and catches the common failure
✅14
whats the lot
lot bought purity assay/label
A-2418 2025-03 99.1% 9.6 / 10mg
A-2601 2025-08 98.7% 9.8 / 10mg
B-0114 2026-01 99.3% 9.4 / 10mg
B-0329 2026-04 98.9% 9.9 / 10mgfollow up what interests me is when the gap goes the same direction every time. once is noise, three times is a pattern
🙏9
i told JEEP about a result they would not have liked and they did not argue. credit where it is due
thats a fill problem
my result contradicts the supplier certificate, do i tell them
weigh it first
a single sample tells you about a single vial. that is genuinely all it tells you
assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem
is a purity-only test worth the money if underfill is the common failure
my sheet has 5 lots from CPC with a spread under a point, which is tight
underfill is more common than impurity. if you only test purity you are testing the less likely failure
follow up coming back after 7 months with a follow up result, where do i put it
nice result
if you are testing to settle an argument you will not settle it with n of 1
🧊14🎉6❤️10