vialroom

#test-results 2025-03-29

Saturday52 messages13 participantstimes are UTC
Highlights from this day
  • split_shipment — a supplier disputing a result is rare here and it has never gone well for the supplier 12:20
  • HPLC_Hank — weigh the vial before you reconstitute. it costs nothing and catches the common failure 12:34
  • forty_five_kg — quick one is quantity testing available as a separate thing or bundled 17:29
SS

a point or two between the certificate and an independent result is inside what two labs disagree by

whats the lot

VO

my read after three years of this: purity is mostly fine across the market and fill consistency is where suppliers differ, we shall see

DE

underfill is more common than impurity. if you only test purity you are testing the less likely failure, i could be wrong

SS

a supplier disputing a result is rare here and it has never gone well for the supplier

🧪29⚠️1
DE

while im here a single sample tells you about a single vial. that is genuinely all it tells you, thats one data point

HH

weigh the vial before you reconstitute. it costs nothing and catches the common failure

[edited]
lot        bought    purity   assay/label
A-2418     2025-03   99.1%    9.6 / 10mg
A-2601     2025-08   98.7%    9.8 / 10mg
B-0114     2026-01   99.3%    9.4 / 10mg
B-0329     2026-04   98.9%    9.9 / 10mg

attach the pdf

my sheet has 4 lots from TFC with a spread under a point, which is tight, anyway
a single sample tells you about a single vial. that is genuinely all it tells you

[edited]
VO

is it worth testing if the vial has already been through a warm transit

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HH

do the results in this channel skew because people test when suspicious

the results in this channel skew because people test when they are suspicious. that is selection bias and it is real

TT

98.1 against a certificate of 97.4 is fine. the same supplier landing low four times in a row is a question

FF

i told KP about a result they would not have liked and they did not argue. credit where it is due

FF

a result without a lot number and a purchase date is an anecdote with a pdf attached

HH

how much does sample handling on my end affect the number

FF

post the lot, the purchase month, the lab, the number, and what you were expecting. that makes it useful later

HH

how many lots do you need before you can say anything about a supplier

MC

for the archive i have never regretted spending the money on a test. i have regretted not testing twice

AB

i test roughly every tenth vial. it is a sampling strategy, not paranoia

*Medutest not the other one

FN

the widest spread in my data is about 2.6 percentage points across five lots from one supplier

FN

one bad test does not condemn a supplier. one good test does not clear one. both halves get ignored equally

FN

what interests me is when the gap goes the same direction every time. once is noise, three times is a pattern, ask me again in a month

if the vial has been through a bad transit you are testing the transit as much as the supplier

HH

if you are testing to settle an argument you will not settle it with n of 1

quantity testing is usually a separate line item and it is the one worth paying for

VO

the honest limits: hobby chain of custody is weak and any result here should be read with that in mind

VB

Purity check: no report on file for lot G-0641. Nothing logged either way.

SS

i had a result i am fairly sure was a handling error on my side and i logged it as such

FF

log the boring results too. a channel that only records failures produces a false picture

SS

quick one assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem

ok so whats the underfill rate people are actually seeing

test it again

FF

quick one is quantity testing available as a separate thing or bundled

🎉10😂7
AB

my vial assayed under label but the purity was fine, which matters more

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