if the vial has been through a bad transit you are testing the transit as much as the supplier
#test-results 2025-08-11
Monday29 messages7 participantstimes are UTC
Highlights from this day
- drawup_dee — assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem 20:22
- a1c_lag — how much does sample handling on my end affect the number 21:04
- turnaround_tam — sample handling on your end absolutely affects it. draw cleanly, ship fast, do not let it sit warm 22:09
my read after three years of this: purity is mostly fine across the market and fill consistency is where suppliers differ
💀5🤝1⚠️2
my vial assayed under label but the purity was fine, which matters more
one data point
assay under label with good purity means you got less of the right thing. that is a fill problem, not a synthesis problem
👀7✅15🧪7
when did you buy it
lot bought purity assay/label
A-2418 2025-03 99.1% 9.6 / 10mg
A-2601 2025-08 98.7% 9.8 / 10mg
B-0114 2026-01 99.3% 9.4 / 10mg
B-0329 2026-04 98.9% 9.9 / 10mgthats not great
log the boring ones
whats the lot
does anyone log the negative results, the boring ones
for the archive the results in this channel skew because people test when they are suspicious. that is selection bias and it is real, i have it written down somewhere
unrelated but update from 17 months ago: retested the same supplier, result came back better, logged both
weigh the vial before you reconstitute. it costs nothing and catches the common failure
[edited]how much does sample handling on my end affect the number
🙏17
my sheet has 6 lots from SGN with a spread under a point, which is tight, ask me again in a month
if you are testing to settle an argument you will not settle it with n of 1
Inter-lab diff for lot B-0114: 99.4% vs 97.4%. Within expected range.
how do you post a result so it is actually useful to somebody in a year
nice result
a result without a lot number and a purchase date is an anecdote with a pdf attached
i told BCH about a result they would not have liked and they did not argue. credit where it is due
thats a fill problem
do you test every order or sample it
sample handling on your end absolutely affects it. draw cleanly, ship fast, do not let it sit warm
🙏3🧪4📈12
one bad test does not condemn a supplier. one good test does not clear one. both halves get ignored equally, your mileage will differ
log the lot number
| Evidence | Counts? |
|---|---|
| Independent report, lot you bought, lot number legible | yes |
| Independent report, no lot number | no |
| Supplier certificate only | no |
| Screenshot of a report | no |
| Blinded pooled submission | yes, for the pool |
| A friend who said it was fine | no |
for the archive what interests me is when the gap goes the same direction every time. once is noise, three times is a pattern
post the lot, the purchase month, the lab, the number, and what you were expecting. that makes it useful later, anyway
whats the worst result anyone has logged and what happened next
a result without a lot number and a purchase date is an anecdote with a pdf attached
🔥7