vialroom

#tirzepatide 2024-01-23

Tuesday15 messages4 participantstimes are UTC
Highlights from this day
  • vial_ledger — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, your mileage will differ 17:48
  • vial_ledger — i argued the sweet spot was nonsense and then spent 7 months at 7.5 not needing more 19:12
  • deadspace — the sweet spot argument is really about effect per side effect, not a magic number plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound… 20:03
  • slow.taper — is 7.5 really the sweet spot or is that just channel folklore 20:12

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, your mileage will differ

VL

changed my mind about needing 15, i was chasing a number rather than an outcome, for what its worth

DE

at 12 my appetite is gone entirely, did anyone go down rather than up

VL

i argued the sweet spot was nonsense and then spent 7 months at 7.5 not needing more

transit-times.csv
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VL

if youre coming off semaglutide the honest answer is start low and find out, theres no table

GIP plus GLP-1

💀4❤️1

start low anyway

ST

the 2.5 to 5 step was the roughest one for me and everything after was easier

DE

the trials titrated every four weeks to a target, most people here stop at whatever works

the sweet spot argument is really about effect per side effect, not a magic number
plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound specific

LM

update on the earlier thing SURMOUNT-1 versus SURPASS-2, which one was the weight trial