#tirzepatide 2024-04-12

Friday13 messages4 participantstimes are UTC

Highlights from this day

tenpence — coming off semaglutide, is there a conversion or do i restart at 2.5 15:31
lean_mass_lex — the GI difference held for me right up to 15, which isnt what a couple of people here found, someone check my working 15:33
bea_reconstitutes — did anybody switch back to semaglutide after trying this the 2.5 to 5 step was the roughest one for me and everything after was easier 15:36
apob_over_ldl — dual agonist, GIP as well as GLP-1, thats the whole difference in one line 16:09
apob_over_ldl — went back to semaglutide after 18 months because the cost difference mattered more than the GI 16:12

does the GIP arm actually explain the easier nausea or is that hand waving

coming off semaglutide, is there a conversion or do i restart at 2.5

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

the GI difference held for me right up to 15, which isnt what a couple of people here found, someone check my working

did anybody switch back to semaglutide after trying this
the 2.5 to 5 step was the roughest one for me and everything after was easier

changed my mind about needing 15, i was chasing a number rather than an outcome

no clean conversion

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

📈1🙏9

SURMOUNT is weight

went back to semaglutide after 18 months because the cost difference mattered more than the GI

same plateau here

if youre coming off semaglutide the honest answer is start low and find out, theres no table

40 units of a 10 solution is a lot of volume and i check that one twice every single time

there is no clean conversion between the two, anyone giving you a ratio is guessing