#tirzepatide 2024-10-20

Sunday20 messages5 participantstimes are UTC

Highlights from this day

chlorhex — coming off semaglutide, is there a conversion or do i restart at 2.5 19:33
lean_mass_lex — how did people handle the 2.5 to 5 jump 19:49
chlorhex — the 2.5 to 5 step was the roughest one for me and everything after was easier the sweet spot argument is really about effect per side effect, not a magic number 20:30
group_buy_gwen — how many weeks at 7.5 before you knew it was enough 20:57
lean_mass_lex — is there a reason to titrate slower than the four week schedule i argued the sweet spot was nonsense and then spent 22 months at 7.5 not needing more 21:33

coming off semaglutide, is there a conversion or do i restart at 2.5

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

chlorhexmod19:46

*2ml not 2.5

lean_mass_lex 19:49

how did people handle the 2.5 to 5 jump

😂10🧊1

lean_mass_lex 20:03

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up

chlorhexmod20:13

is 7.5 really the sweet spot or is that just channel folklore

💀1

chlorhexmod20:27

*that should say weekly

the 2.5 to 5 step was the roughest one for me and everything after was easier
the sweet spot argument is really about effect per side effect, not a magic number

lean_mass_lex SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix…

split_the_cost 20:32

the switch felt like a step down at first and then caught up around week 11

lean_mass_lex 20:49

i sat at 7.5 for 4 months and never needed more, which is where the folklore comes from

15 is the top

chlorhexmod20:52

held 10 for 23 months and lost 5kg over that stretch, slow and boring and fine

GIP plus GLP-1

group_buy_gwen 20:57

how many weeks at 7.5 before you knew it was enough

👍6⚠️5

underfill_uma 21:00

folklore probably

underfill_uma 21:10

follow up licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

checked the units twice

group_buy_gwen 21:12

12 did nothing extra over 10 for me and that still holds a year later

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

lean_mass_lex 21:18

titrate slow

lean_mass_lex 21:33

is there a reason to titrate slower than the four week schedule
i argued the sweet spot was nonsense and then spent 22 months at 7.5 not needing more