vialroom

#tirzepatide 2024-10-31

Thursday21 messages5 participantstimes are UTC
Highlights from this day
  • igf_one_ivy — dual agonist, GIP as well as GLP-1, thats the whole difference in one line, n of 1 obviously 18:42
  • net_peptide — for the archive how did people handle the 2.5 to 5 jump 19:18
  • a1c_lag — at 15 my appetite went completely and i dropped back a step, eating nothing isnt a win 20:04
NP

coming off semaglutide, is there a conversion or do i restart at 2.5

why does everyone talk about 7.5 and not 10

VB

Inter-lab diff for lot A-2601: 98.6% vs 96.8%. Within expected range.

start low anyway

IO

went back to semaglutide after 12 months because the cost difference mattered more than the GI

NP

the switch felt like a step down at first and then caught up around week 14
40 units of a 10 solution is a lot of volume and i check that one twice every single time

sorry to jump in the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

IO

dual agonist, GIP as well as GLP-1, thats the whole difference in one line, n of 1 obviously

🔥214
A1

whats the plateau pattern here, same as semaglutide or different

NP

for the archive how did people handle the 2.5 to 5 jump

peptidemeter-summary-e-2205.pdf
2 pages · 835 KB · not retained in the public archive

quick one SURMOUNT-1 versus SURPASS-2, which one was the weight trial

does the GIP arm actually explain the easier nausea or is that hand waving

€94 for a 20 vial is roughly what ive paid for the last year

at 15 my appetite went completely and i dropped back a step, eating nothing isnt a win

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)