15 is the top
💀9⚠️9👍6
#tirzepatide 2024-11-16
Saturday38 messages8 participantstimes are UTC
Highlights from this day
- belfast_bac — is SURMOUNT-OSA the sleep apnoea one 16:39
- snac_and_water — i sat at 7.5 for 10 months and never needed more, which is where the folklore comes from, anyway 17:11
- sulphur_burp — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 18:40
- baseline_drift — the switch felt like a step down at first and then caught up around week 28 19:05
12 did nothing extra over 10 for me and that still holds a year later
switched last year
👍9
folklore probably
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
changed my mind about needing 15, i was chasing a number rather than an outcome
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, thats just me
$72 for a 40 vial is roughly what ive paid for the last year
the 2.5 to 5 step was the roughest one for me and everything after was easier
🧪1
start low anyway
[edited]is SURMOUNT-OSA the sleep apnoea one
🙏15
anyone got a 2 recon they like for the 5 vials
the switch felt like a step down at first and then caught up around week 16
i sat at 7.5 for 10 months and never needed more, which is where the folklore comes from, anyway
fridge-thermometer.png
800 × 800 · 818 KB · not retained in the public archive
no clean conversion
📉11📈11🤝3
did going from 0.5 semaglutide to 5 of this feel like a step down for anyone
GIP plus GLP-1
the sweet spot thing is survivorship, the people it worked for stayed and said so
ok so there is no clean conversion between the two, anyone giving you a ratio is guessing
no gap when i switched, took the last semaglutide dose and started this a week later
is the sweet spot argument about effect or about side effects
the two compounds arent interchangeable week for week even if the effect ends up similar
how did people handle the 2.5 to 5 jump
the 2.5 to 5 step was the roughest one for me and everything after was easier
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
🎉7💀5👀3
40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
while im here went back to semaglutide after 22 months because the cost difference mattered more than the GI
SURMOUNT is weight
10 was enough
💀4📉1
switched from 0.25 semaglutide and started at 2.5, took the slow route, never regretted it, ask me again in a month
5 did nothing
the switch felt like a step down at first and then caught up around week 28
👀1🙏2🎉3
does the GIP arm actually explain the easier nausea or is that hand waving
[edited]easier gi for me
same plateau here
checked the units twice
held 10 for 17 months and lost 41kg over that stretch, slow and boring and fine
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
7.5 gang
if youre coming off semaglutide the honest answer is start low and find out, theres no table