vialroom

#tirzepatide 2024-12-15

Sunday37 messages9 participantstimes are UTC
Highlights from this day
  • cold_start_cy — $120 for a 10 vial is roughly what ive paid for the last year 15:18
  • secretagogue_sy — did going from 15 semaglutide to 5 of this feel like a step down for anyone no gap when i switched, took the last semaglutide dose and started this a week later 15:49
  • underfill_uma — changed my mind about needing 15, i was chasing a number rather than an outcome 17:08
  • secretagogue_sy — at 15 the GI came back for me, so my easier profile claim only applies below that 17:59
CS

right so i argued the sweet spot was nonsense and then spent 3 months at 7.5 not needing more

went back to semaglutide after 20 months because the cost difference mattered more than the GI

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

my Janoshik result on a WWB vial came in at 99.2 which is why i keep buying from them

UU

there is no clean conversion between the two, anyone giving you a ratio is guessing

switched last year

CS

the 2 vial in 3ml gives 4mg/ml which puts 15 on 50 units, nice round numbers

CS

$120 for a 10 vial is roughly what ive paid for the last year

Cited study
Tirzepatide for Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA)
New England Journal of Medicine · 2024
AHI as the primary endpoint, with and without PAP therapy.
VI

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

SS

did going from 15 semaglutide to 5 of this feel like a step down for anyone
no gap when i switched, took the last semaglutide dose and started this a week later

📈7📉5

held 10 for 20 months and lost 5kg over that stretch, slow and boring and fine

BS

im at 5 and thinking about 2.4, did anyone gain anything from that step

VB

Batch lookup E-2205: 5 independent reports on file, earliest 2024-03-05.

SS

update on the earlier thing the switch felt like a step down at first and then caught up around week 15

[edited]

5 was where i first noticed it properly, 2.5 did almost nothing for me

UU

changed my mind about needing 15, i was chasing a number rather than an outcome

😂3💀14🙏14

dual agonist, GIP as well as GLP-1, thats the whole difference in one line

anyone stopped at 10 and stayed there for months

UU

the trials titrated every four weeks to a target, most people here stop at whatever works

transit-times.csv
923 rows · not retained in the public archive
SS

at 15 the GI came back for me, so my easier profile claim only applies below that

🙏1🤝2📉11
UU

quick one if youre coming off semaglutide the honest answer is start low and find out, theres no table

SS

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

💀10
UU

switched from 5 semaglutide and started at 2.5, took the slow route, never regretted it

RS

genuine question the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

DD

no gap when i switched, took the last semaglutide dose and started this a week later