held 10 for 8 months and lost 43kg over that stretch, slow and boring and fine
#tirzepatide 2025-03-04
Tuesday23 messages5 participantstimes are UTC
Highlights from this day
- taper_tess — the sweet spot argument is really about effect per side effect, not a magic number the trials titrated every four weeks to a target, most people here stop at whatever… 13:11
- underfill_uma — anyone tracked whether the GI difference held at the top doses 13:12
- hair_month_four — at 0.25 my appetite went completely and i dropped back a step, eating nothing isnt a win licensed top is 15 weekly, past that is not a licensed dose and nobody here… 13:51
- tail_factor — if youre coming off semaglutide the honest answer is start low and find out, theres no table 40 units of a 10 solution is a lot of volume and i check that one twice… 14:19
- nausea_window — i went to 15 and came back to 10, more suppression wasnt more useful for me, your mileage will differ 14:21
the sweet spot argument is really about effect per side effect, not a magic number
the trials titrated every four weeks to a target, most people here stop at whatever works
anyone tracked whether the GI difference held at the top doses
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the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
10 was enough
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dual agonist, GIP as well as GLP-1, thats the whole difference in one line
i argued the sweet spot was nonsense and then spent 18 months at 7.5 not needing more
at 0.25 my appetite went completely and i dropped back a step, eating nothing isnt a win
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
hair_month_fouri argued the sweet spot was nonsense and then spent 18 months at 7.5 not needing more
is the 10 vial the common one or do people use 30
is SURMOUNT-OSA the sleep apnoea one
€94 for a 10 vial is roughly what ive paid for the last year
SURMOUNT is weight
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SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
changed my mind about needing 15, i was chasing a number rather than an outcome
there is no clean conversion between the two, anyone giving you a ratio is guessing
if youre coming off semaglutide the honest answer is start low and find out, theres no table
40 units of a 10 solution is a lot of volume and i check that one twice every single time
i went to 15 and came back to 10, more suppression wasnt more useful for me, your mileage will differ
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i sat at 7.5 for 22 months and never needed more, which is where the folklore comes from
went back to semaglutide after 26 months because the cost difference mattered more than the GI
*VendorInvestigate not the other one
the sweet spot thing is survivorship, the people it worked for stayed and said so
start low anyway
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the two compounds arent interchangeable week for week even if the effect ends up similar