#tirzepatide 2025-03-08

no gap when i switched, took the last semaglutide dose and started this a week later, thats just me
the 40 vial in 1.5ml gives 5mg/ml which puts 12 on 12 units, nice round numbers

changed my mind about needing 15, i was chasing a number rather than an outcome
£38 for a 30 vial is roughly what ive paid for the last year

how did people handle the 2.5 to 5 jump

is 7.5 really the sweet spot or is that just channel folklore

if youre coming off semaglutide the honest answer is start low and find out, theres no table

SURMOUNT is weight

there is no clean conversion between the two, anyone giving you a ratio is guessing, n of 1 obviously

does switching from semaglutide need a gap or do you just start

does the GIP arm actually explain the easier nausea or is that hand waving

does the appetite effect feel different or just stronger

my VendorInvestigate result on a Homopeptide vial came in at 99 which is why i keep buying from them

update on the earlier thing did anyone go past 15 and was there any point to it

the sweet spot argument is really about effect per side effect, not a magic number, anyway

update on the earlier thing im at 15 and thinking about 0.5, did anyone gain anything from that step
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

15 is the top

update on the earlier thing i log everything and my appetite curve looks flatter across the week than my semaglutide log did

follow up at 1.7 my appetite went completely and i dropped back a step, eating nothing isnt a win

how many weeks at 7.5 before you knew it was enough

anyone stopped at 10 and stayed there for months

the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

Recon calculator: 2mg in 2ml = 4mg/ml.

the trials titrated every four weeks to a target, most people here stop at whatever works

easier gi for me

switched last year

follow up the two compounds arent interchangeable week for week even if the effect ends up similar

start low anyway

ok so i sat at 7.5 for 20 months and never needed more, which is where the folklore comes from

SURMOUNT-1 versus SURPASS-2, which one was the weight trial

7.5 gang

i argued the sweet spot was nonsense and then spent 21 months at 7.5 not needing more

plateaued at 14 weeks the same way i did on semaglutide, so i doubt its compound specific
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact

for the archive the 5 vial in 2.5ml gives 2.5mg/ml which puts 5 on 40 units, nice round numbers, your mileage will differ
plateaued at 33 weeks the same way i did on semaglutide, so i doubt its compound specific

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, i think

did anyone find the GI easier than semaglutide at an equivalent effect

40 units of a 10 solution is a lot of volume and i check that one twice every single time

held 10 for 3 months and lost 6kg over that stretch, slow and boring and fine, anyway