the trials titrated every four weeks to a target, most people here stop at whatever works
#tirzepatide 2025-04-14
Monday25 messages6 participantstimes are UTC
Highlights from this day
- cat_on_the_tray — coming back to this is the sweet spot argument about effect or about side effects 18:23
- bea_reconstitutes — i log everything and my appetite curve looks flatter across the week than my semaglutide log did 18:38
- blind_submit — anyone stopped at 10 and stayed there for months 18:39
- bea_reconstitutes — restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists 19:27
- bea_reconstitutes — im at 2.5 and thinking about 1.7, did anyone gain anything from that step 19:38
changed my mind about needing 15, i was chasing a number rather than an outcome
coming back to this is the sweet spot argument about effect or about side effects
🎉9
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)💀2😂5🧊5
anyone stopped at 10 and stayed there for months
📈15
switched last year
folklore probably
anyone tracked whether the GI difference held at the top doses
does the GIP arm actually explain the easier nausea or is that hand waving
5 did nothing
👀11
at 1 my appetite is gone entirely, did anyone go down rather than up
SURMOUNT-1 versus SURPASS-2, which one was the weight trial
restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
im at 2.5 and thinking about 1.7, did anyone gain anything from that step
💀2🔥3❤️9
there is no clean conversion between the two, anyone giving you a ratio is guessing
switched from 2.4 semaglutide and started at 2.5, took the slow route, never regretted it
start low anyway
no gap when i switched, took the last semaglutide dose and started this a week later
did going from 5 semaglutide to 5 of this feel like a step down for anyone
same plateau here
checked the units twice
no clean conversion
£55 for a 30 vial is roughly what ive paid for the last year
7.5 gang