vialroom

#tirzepatide 2025-05-24

Saturday15 messages6 participantstimes are UTC
Highlights from this day
  • seven_five_sweet — right so restarted at 2.5 after 11 months off and the first two doses reminded me why titration exists 13:35
  • VialBot — Testing queue: 6 submissions open, 131 awaiting dispatch. 13:58
  • seven_five_sweet — SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted, i have it written down somewhere 14:06
  • month_six_me — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, not advice obviously 14:54
  • split_shipment — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, not advice obviously 15:00
SF

right so restarted at 2.5 after 11 months off and the first two doses reminded me why titration exists

Cited study
Tirzepatide for Obstructive Sleep Apnea and Obesity (SURMOUNT-OSA)
New England Journal of Medicine · 2024
AHI as the primary endpoint, with and without PAP therapy.
FF

ok so switched from 2.5 semaglutide and started at 2.5, took the slow route, never regretted it

SURMOUNT is weight

FF

licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does

VB

Testing queue: 6 submissions open, 131 awaiting dispatch.

🔥10
SF

SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted, i have it written down somewhere

whats the plateau pattern here, same as semaglutide or different

[edited]

SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up, not advice obviously

MS

the 5 vial in 5ml gives 10mg/ml which puts 15 on 10 units, nice round numbers

TA

if youre coming off semaglutide the honest answer is start low and find out, theres no table