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#tirzepatide 2025-06-03

Tuesday25 messages5 participantstimes are UTC
Highlights from this day
  • noct.titrate — unrelated but i went to 15 and came back to 10, more suppression wasnt more useful for me 20:47
  • see_a_clinician — whats the top licensed dose, 15 or does it go higher at 15 the GI came back for me, so my easier profile claim only applies below that 21:04
  • HPLC_Hank — update on the earlier thing does the appetite effect feel different or just stronger SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however… 21:46
  • cagri_curious — the sweet spot thing is survivorship, the people it worked for stayed and said so 22:22
  • see_a_clinician — my PeptideMeter result on a JEEP vial came in at 99 which is why i keep buying from them 22:26
NT

the 10 vial in 5ml gives 10mg/ml which puts 15 on 8 units, nice round numbers

im at 2 and thinking about 15, did anyone gain anything from that step

unrelated but i went to 15 and came back to 10, more suppression wasnt more useful for me

🧊9

the two compounds arent interchangeable week for week even if the effect ends up similar

if youre coming off semaglutide the honest answer is start low and find out, theres no table, ymmv

GI was noticeably easier for me than semaglutide at what felt like the same appetite effect, not advice obviously

SA

whats the top licensed dose, 15 or does it go higher
at 15 the GI came back for me, so my easier profile claim only applies below that

*that should say weekly

HH

40 units of a 5 solution is a lot of volume and i check that one twice every single time

NA

quick one did anyone find the GI easier than semaglutide at an equivalent effect

the trials titrated every four weeks to a target, most people here stop at whatever works, take that with a pinch of salt

slightly off topic but does switching from semaglutide need a gap or do you just start

update on the earlier thing does the appetite effect feel different or just stronger
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

did anyone go past 15 and was there any point to it

SA

i log everything and my appetite curve looks flatter across the week than my semaglutide log did

CC

the switch felt like a step down at first and then caught up around week 2

CC

the sweet spot thing is survivorship, the people it worked for stayed and said so

🔥9😂2⚠️3
SA

my PeptideMeter result on a JEEP vial came in at 99 which is why i keep buying from them