7.5 gang
#tirzepatide 2025-08-14
Thursday18 messages4 participantstimes are UTC
Highlights from this day
15 is the top
is there a reason to titrate slower than the four week schedule
SURMOUNT-OSA was the sleep apnoea trial and it is not a weight headline however its quoted
anyone tracked whether the GI difference held at the top doses
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the switch felt like a step down at first and then caught up around week 23
5 was where i first noticed it properly, 2.5 did almost nothing for me, your mileage will differ
*2ml not 2.5
12 did nothing extra over 10 for me and that still holds a year later
vial-kp-0925-front.png
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Reminder for plateau_pen: dose day is today. Set 7 days ago.
at 15 the GI came back for me, so my easier profile claim only applies below that, take that with a pinch of salt
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
follow up went back to semaglutide after 26 months because the cost difference mattered more than the GI
folklore probably
[edited]easier gi for me
plateaued at 19 weeks the same way i did on semaglutide, so i doubt its compound specific
Recon calculator: 15mg in 1.5ml = 4mg/ml.
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Testing queue: 4 submissions open, 50 awaiting dispatch.
dual agonist, GIP as well as GLP-1, thats the whole difference in one line