GIP plus GLP-1
#tirzepatide 2025-08-26
Tuesday27 messages7 participantstimes are UTC
Highlights from this day
- monoisotopic — slightly off topic but there is no clean conversion between the two, anyone giving you a ratio is guessing 18:22
- VialBot — Archive lookup: monoisotopic first appears in this channel on 2025-03-12. 18:59
- bea_reconstitutes — i argued the sweet spot was nonsense and then spent 19 months at 7.5 not needing more, i could be wrong 19:50
- monoisotopic — did anyone find the GI easier than semaglutide at an equivalent effect 20:05
40 units of a 2.5 solution is a lot of volume and i check that one twice every single time
same plateau here
folklore probably
did going from 2.5 semaglutide to 5 of this feel like a step down for anyone
how did people handle the 2.5 to 5 jump
slightly off topic but there is no clean conversion between the two, anyone giving you a ratio is guessing
slightly off topic but plateaued at 13 weeks the same way i did on semaglutide, so i doubt its compound specific
did anyone go past 15 and was there any point to it
anyone stopped at 10 and stayed there for months
i went to 15 and came back to 10, more suppression wasnt more useful for me, take that with a pinch of salt
Archive lookup: monoisotopic first appears in this channel on 2025-03-12.
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
🎉1
if youre coming off semaglutide the honest answer is start low and find out, theres no table
15 is the top
*Medutest not the other one
i argued the sweet spot was nonsense and then spent 19 months at 7.5 not needing more, i could be wrong
✅13👍5
at 1 my appetite is gone entirely, did anyone go down rather than up
while im here how long before the dual thing was noticeable to you
the two compounds arent interchangeable week for week even if the effect ends up similar
is the sweet spot argument about effect or about side effects
did anyone find the GI easier than semaglutide at an equivalent effect
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)🙏1😂5
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
12 did nothing extra over 10 for me and that still holds a year later
is there a reason to titrate slower than the four week schedule
follow up anyone got a 10 recon they like for the 5 vials
start low anyway