same plateau here
#tirzepatide 2025-10-19
Sunday38 messages8 participantstimes are UTC
Highlights from this day
- half_life_hal — went back to semaglutide after 7 months because the cost difference mattered more than the GI 10:28
- ring_size_down — my VendorInvestigate result on a GL Biochem vial came in at 99.2 which is why i keep buying from them the switch felt like a step down at first and then caught up… 12:26
- apob_over_ldl — i log everything and my appetite curve looks flatter across the week than my semaglutide log did, we shall see 12:28
- panel_before_after — i went to 15 and came back to 10, more suppression wasnt more useful for me 14:06
whats the plateau pattern here, same as semaglutide or different
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
went back to semaglutide after 7 months because the cost difference mattered more than the GI
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switched from 2 semaglutide and started at 2.5, took the slow route, never regretted it
whats the top licensed dose, 15 or does it go higher
im at 1.7 and thinking about 0.5, did anyone gain anything from that step
held 10 for 14 months and lost 20kg over that stretch, slow and boring and fine
40 units of a 10 solution is a lot of volume and i check that one twice every single time
SURMOUNT is weight
switched last year
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folklore probably
start low anyway
the switch felt like a step down at first and then caught up around week 27
did anybody switch back to semaglutide after trying this
the 2.5 to 5 step was the roughest one for me and everything after was easier
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5 did nothing
while im here plateaued at 4 weeks the same way i did on semaglutide, so i doubt its compound specific
10 was enough
coming back to this if youre coming off semaglutide the honest answer is start low and find out, theres no table, we shall see
the sweet spot argument is really about effect per side effect, not a magic number
restarted at 2.5 after 19 months off and the first two doses reminded me why titration exists
[edited]my VendorInvestigate result on a GL Biochem vial came in at 99.2 which is why i keep buying from them
the switch felt like a step down at first and then caught up around week 32
i log everything and my appetite curve looks flatter across the week than my semaglutide log did, we shall see
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coming off semaglutide, is there a conversion or do i restart at 2.5
the two compounds arent interchangeable week for week even if the effect ends up similar
the two compounds arent interchangeable week for week even if the effect ends up similar
at 15 the GI came back for me, so my easier profile claim only applies below that
no gap when i switched, took the last semaglutide dose and started this a week later
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
i went to 15 and came back to 10, more suppression wasnt more useful for me
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)how did people handle the 2.5 to 5 jump
i argued the sweet spot was nonsense and then spent 22 months at 7.5 not needing more
licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does, not advice obviously
the GI difference held for me right up to 15, which isnt what a couple of people here found
12 did nothing extra over 10 for me and that still holds a year later
7.5 gang
€55 for a 40 vial is roughly what ive paid for the last year
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titrate slow
On this day 5 years ago this channel logged 66 messages.
coming back to this the trials titrated every four weeks to a target, most people here stop at whatever works, i think