SURMOUNT is weight
#tirzepatide 2025-12-14
Sunday16 messages3 participantstimes are UTC
Highlights from this day
- alcohol_hits — the trials titrated every four weeks to a target, most people here stop at whatever works 20:13
- alcohol_hits — GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 20:15
- alcohol_hits — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 20:18
unrelated but at 0.5 my appetite went completely and i dropped back a step, eating nothing isnt a win
5 did nothing
does the GIP arm actually explain the easier nausea or is that hand waving
the trials titrated every four weeks to a target, most people here stop at whatever works
🎉15🧪18💀6
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
the sweet spot thing is survivorship, the people it worked for stayed and said so
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
😂6🔥1
7.5 gang
at 15 the GI came back for me, so my easier profile claim only applies below that
switched last year
😂1🤝7✅1
is 7.5 really the sweet spot or is that just channel folklore
did going from 15 semaglutide to 5 of this feel like a step down for anyone
40 units of a 2 solution is a lot of volume and i check that one twice every single time
checked the units twice
the GI difference held for me right up to 15, which isnt what a couple of people here found, someone check my working