at 12 my appetite went completely and i dropped back a step, eating nothing isnt a win
#tirzepatide 2025-12-21
Sunday27 messages6 participantstimes are UTC
Highlights from this day
- madrid_mg — is 7.5 really the sweet spot or is that just channel folklore 20:14
- drawup_dee — at 15 the GI came back for me, so my easier profile claim only applies below that 20:25
- rezept_rolf — does the appetite effect feel different or just stronger 21:22
- cold_chain_cmdr — plateaued at 7 weeks the same way i did on semaglutide, so i doubt its compound specific 22:29
checked the units twice
🎉12
no clean conversion
7.5 gang
🎉17🧊2🧪17
is 7.5 really the sweet spot or is that just channel folklore
👍3👀15
titrate slow
at 15 the GI came back for me, so my easier profile claim only applies below that
💀14
start low anyway
5 did nothing
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)sorry to jump in SURMOUNT-1 versus SURPASS-2, which one was the weight trial
did anyone find the GI easier than semaglutide at an equivalent effect
at 2 my appetite is gone entirely, did anyone go down rather than up
[edited]easier gi for me
10 was enough
restarted at 2.5 after 20 months off and the first two doses reminded me why titration exists, from memory
there is no clean conversion between the two, anyone giving you a ratio is guessing
does the appetite effect feel different or just stronger
📉7
GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
SURMOUNT is weight
the sweet spot thing is survivorship, the people it worked for stayed and said so
while im here the GIP explanation for easier nausea is plausible and i still treat it as a story not a fact
40 units of a 5 solution is a lot of volume and i check that one twice every single time
plateaued at 7 weeks the same way i did on semaglutide, so i doubt its compound specific
😂1💀8🧪9
switched last year
i went to 15 and came back to 10, more suppression wasnt more useful for me