start low anyway
#tirzepatide 2026-03-10
- net_peptide — SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up 14:39
- seizure_letter — the 2.5 to 5 step was the roughest one for me and everything after was easier 15:36
- net_peptide — coming back to this GI was noticeably easier for me than semaglutide at what felt like the same appetite effect 17:15
the sweet spot thing is survivorship, the people it worked for stayed and said so
SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
the GI difference held for me right up to 15, which isnt what a couple of people here found
while im here if youre coming off semaglutide the honest answer is start low and find out, theres no table
restarted at 2.5 after 3 months off and the first two doses reminded me why titration exists
easier gi for me
[edited]did anyone find the GI easier than semaglutide at an equivalent effect
whats the top licensed dose, 15 or does it go higher
coming back to this the two compounds arent interchangeable week for week even if the effect ends up similar
the trials titrated every four weeks to a target, most people here stop at whatever works
7.5 gang
how many weeks at 7.5 before you knew it was enough
switched last year
same plateau here
the 2.5 to 5 step was the roughest one for me and everything after was easier
how did people handle the 2.5 to 5 jump
coming back to this i went to 15 and came back to 10, more suppression wasnt more useful for me
12 did nothing extra over 10 for me and that still holds a year later
is there a reason to titrate slower than the four week schedule
how long before the dual thing was noticeable to you
10 was enough
coming back to this GI was noticeably easier for me than semaglutide at what felt like the same appetite effect
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)5 was where i first noticed it properly, 2.5 did almost nothing for me
40 units of a 5 solution is a lot of volume and i check that one twice every single time
held 10 for 14 months and lost 47kg over that stretch, slow and boring and fine
went back to semaglutide after 16 months because the cost difference mattered more than the GI
GIP plus GLP-1
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)for the archive is 7.5 really the sweet spot or is that just channel folklore
checked the units twice
why does everyone talk about 7.5 and not 10
titrate slow
5 did nothing
back after 15 months, do i restart at 2.5 or pick up near where i left off
does the appetite effect feel different or just stronger
anyone tracked whether the GI difference held at the top doses
*PeptideMeter not the other one
dual agonist, GIP as well as GLP-1, thats the whole difference in one line
changed my mind about needing 15, i was chasing a number rather than an outcome
does switching from semaglutide need a gap or do you just start