i went to 15 and came back to 10, more suppression wasnt more useful for me
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#tirzepatide 2026-03-30
Monday40 messages9 participantstimes are UTC
Highlights from this day
- void_volume — i went to 15 and came back to 10, more suppression wasnt more useful for me 14:23
- VialBot — Testing queue: 2 submissions open, 113 awaiting dispatch. 15:07
- VialBot — Channel stats, last 30 days: 36 messages from 18 members. 16:10
- thank_you_year_on — the 2.5 to 5 step was the roughest one for me and everything after was easier 5 was where i first noticed it properly, 2.5 did almost nothing for me 17:06
- birch_bloods — the trials titrated every four weeks to a target, most people here stop at whatever works 17:37
held 10 for 1 months and lost 23kg over that stretch, slow and boring and fine
the GI difference held for me right up to 15, which isnt what a couple of people here found
did anyone go past 15 and was there any point to it
the 20 vial in 5ml gives 4mg/ml which puts 5 on 30 units, nice round numbers
no gap when i switched, took the last semaglutide dose and started this a week later
5 was where i first noticed it properly, 2.5 did almost nothing for me
SURMOUNT is weight
i log everything and my appetite curve looks flatter across the week than my semaglutide log did
switched from 0.25 semaglutide and started at 2.5, took the slow route, never regretted it
coming off semaglutide, is there a conversion or do i restart at 2.5
titrate slow
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dual agonist, GIP as well as GLP-1, thats the whole difference in one line
Testing queue: 2 submissions open, 113 awaiting dispatch.
checked the units twice
the two compounds arent interchangeable week for week even if the effect ends up similar
the switch felt like a step down at first and then caught up around week 25
the sweet spot argument is really about effect per side effect, not a magic number
right so did going from 0.25 semaglutide to 5 of this feel like a step down for anyone
did anyone find the GI easier than semaglutide at an equivalent effect
Channel stats, last 30 days: 36 messages from 18 members.
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switched last year
7.5 gang
does the GIP arm actually explain the easier nausea or is that hand waving
while im here SURMOUNT was the weight programme and SURPASS was diabetes, thats the split people mix up
the 2.5 to 5 step was the roughest one for me and everything after was easier
5 was where i first noticed it properly, 2.5 did almost nothing for me
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)start low anyway
the trials titrated every four weeks to a target, most people here stop at whatever works
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licensed top is 15 weekly, past that is not a licensed dose and nobody here can tell you what it does
folklore probably
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plateaued at 26 weeks the same way i did on semaglutide, so i doubt its compound specific
how did people handle the 2.5 to 5 jump
is the sweet spot argument about effect or about side effects
went back to semaglutide after 19 months because the cost difference mattered more than the GI
i argued the sweet spot was nonsense and then spent 20 months at 7.5 not needing more
40 units of a 10 solution is a lot of volume and i check that one twice every single time
the two compounds arent interchangeable week for week even if the effect ends up similar
does the appetite effect feel different or just stronger
[edited]5 did nothing
[edited]GIP plus GLP-1
how many weeks at 7.5 before you knew it was enough