the sleep apnoea trial enrolled a specific population and reading it across is a stretch
Thread · #tirzepatide · 2026-04-23
comparing your own experience across molecules is the only
Spun off from a message in #tirzepatide on 2026-04-23. 17 messages, 3 participants.
The message this came from
- clothes_size_cass — comparing your own experience across molecules is the only honest comparison anyone in here can make 21:19
my notes across the switch are more useful than anything i remember about it, which is the argument for notes
dexa at baseline
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do people split the weekly on this or is that only a sema thing, sorry if thats been covered
one for the chart people 12 and 10 were indistinguishable for me over a year, and i only know that because i wrote it down at the time, no prize for moving
from my own notes across the switch i stopped tracking daily because the daily number is noise, weekly against a four week average was the only thing that made sense, that is somebody arithmetic, not data
5 did nothing
👀14
no prize for moving
back down to 10
the nausea profile being milder is widely reported here and it is not a universal experience, happy to be told my reading is wrong
the effect felt flatter across the week for me than what i was used to, and that was the main difference i noticed, the population was studied properly
one for the chart people week two of a step is worse than week one for me every single time, which makes the four week rule feel arbitrary
the GI difference held for me right up to 15, which isnt what a couple of people here found
[edited]how much of the difference people describe is dose and how much is the molecule, anyone
🤝5✅2
trial pedantry again, sorry €72 for a 30 vial is roughly what ive paid for the last year
SURMOUNT-1 is the weight trial and the SURPASS programme is the glycaemic one, and people quote them across each other constantly, the middle did more for me
the week of a step change was consistently the worst week for me across the whole ladder, happy to be told my reading is wrong