vialroom

#cagrilintide 2024-10-06

Sunday25 messages6 participantstimes are UTC
Highlights from this day
  • group_buy_gwen — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 15:00
  • mg_per_ml — anyone dosing this on a different day to their semaglutide 15:30
  • mg_per_ml — dosing them on different days made no difference i could detect 19:44
GB

amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist

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TA

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

for the archive £185 for a 20 vial and it lasts me longer than the GLP-1 does at my doses

Cited study
Efficacy and Safety of Cagrilintide in Adults with Overweight or Obesity — Phase 2
The Lancet · 2021
Cagrilintide monotherapy, dose ranging. The combination trials came later.
TA

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

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MP

anyone dosing this on a different day to their semaglutide

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underwhelming honestly

ST

monotherapy did work for me, just slower and smaller than i expected

NT

monotherapy was underwhelming for me and i say that as someone who wanted it to work, your mileage will differ

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RW

the reason nausea reads differently is timing, mine arrived on the second day rather than the first

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coming back to this the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing

NT

update on the earlier thing went slower because the first step gave me two rough days and i took that as information

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NT

the fullness thing is the part people describe differently, food stops being interesting rather than repellent

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NT

2 in 3ml gives 8mg/ml which is what i use, purely because the units come out round

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did the combination change your GI compared to the GLP-1 alone

NT

unrelated but i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something

MP

dosing them on different days made no difference i could detect

[edited]
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