vialroom

#cagrilintide 2024-10-16

Wednesday16 messages5 participantstimes are UTC
Highlights from this day
  • split_dose_sam — changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing 19:08
  • reta_resting_hr — two PeptideMeter results on the same QYB lot came back 99.4 and 96.8, closer than i expected 20:12
  • tenpence — how slow are people titrating this compared to retatrutide 20:14
DE

follow up is anyone running this on its own or is it all CagriSema in here

DE

sorry to jump in anyone stopped the GLP-1 and kept only this

[edited]
SD

changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing

Cited study
Efficacy and Safety of Cagrilintide in Adults with Overweight or Obesity — Phase 2
The Lancet · 2021
Cagrilintide monotherapy, dose ranging. The combination trials came later.
MS

REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work

weekly for me, same day every week, no reason beyond habit

combination GI was worse than either alone for me, which is not what i had read anywhere, from memory

SD

the nausea felt different rather than less, more fullness and less of the queasy wave

SD

i titrated over twice as many weeks as i did on semaglutide and that was right for me

i keep the two on separate days so if something goes wrong i have a chance of knowing which

two PeptideMeter results on the same QYB lot came back 99.4 and 96.8, closer than i expected

🔥3
TE

how slow are people titrating this compared to retatrutide

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did anyone add this to an existing cagrilintide dose rather than starting both