slower than the others
#cagrilintide 2025-04-21
Monday32 messages8 participantstimes are UTC
Highlights from this day
- tarpit_tam — noticed something around week 24 on monotherapy, well after i had given up expecting to 19:43
- VialBot — Assay note: HJ lot SG-1177 reported at 99.4% of label content. 20:21
- escalation_anxiety — REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work 21:25
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
thats the phase 3 one
did the combination change your GI compared to the GLP-1 alone
does the fullness effect fade the way appetite suppression does
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noticed something around week 24 on monotherapy, well after i had given up expecting to
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fullness rather than nausea
anyone dosing this on a different day to their cagrilintide
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is the weekly schedule the same here
dosing them on different days made no difference i could detect
amylin analogue, so its not a GLP-1 at all right
has REDEFINE reported or are people quoting earlier work
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Assay note: HJ lot SG-1177 reported at 99.4% of label content.
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does amylin do something about fullness that the GLP-1 doesnt
CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
$185 for a 30 vial and it lasts me longer than the GLP-1 does at my doses
slightly off topic but the nausea felt different rather than less, more fullness and less of the queasy wave
anyone got two PeptideMeter results on the same WWB lot for this
amylin not glp-1
titrating dead slow
cagrisema thats it
did the nausea feel different to you or just less
lost 13lb over 7 months on the combination and i genuinely cannot apportion it
how many weeks before you noticed anything on monotherapy
i keep the two on separate days so if something goes wrong i have a chance of knowing which
back after 24 months, is monotherapy still a minority thing here
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
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the fullness effect hasnt faded over 18 months, unlike my semaglutide appetite curve
the slower titration in here is community habit as much as anything, the trials had their own schedule
10 in 5ml gives 4mg/ml which is what i use, purely because the units come out round, ymmv
combination for me
did anyone add this to an existing retatrutide dose rather than starting both