cagrisema thats it
#cagrilintide 2025-06-19
Thursday15 messages3 participantstimes are UTC
Highlights from this day
- vial_ledger — the slower titration in here is community habit as much as anything, the trials had their own schedule 19:17
- vial_ledger — amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist 19:20
- vial_ledger — the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, ask me again in a month 19:22
- igf_one_ivy — sorry to jump in combination GI was worse than either alone for me, which is not what i had read anywhere, i have it written down somewhere 19:40
- igf_one_ivy — the fullness thing is the part people describe differently, food stops being interesting rather than repellent 20:15
weekly for me, same day every week, no reason beyond habit
follow up held at 0.25 for 9 months on monotherapy before i touched it again
the slower titration in here is community habit as much as anything, the trials had their own schedule
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist
different not less
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the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair, ask me again in a month
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
is there a reason people titrate this over more weeks than the others
REDEFINE is the trial
sorry to jump in combination GI was worse than either alone for me, which is not what i had read anywhere, i have it written down somewhere
[edited]😂12🤝11
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
separate days
the fullness effect hasnt faded over 18 months, unlike my semaglutide appetite curve
dosing them on different days made no difference i could detect