unrelated but lost 50lb over 5 months on the combination and i genuinely cannot apportion it
#cagrilintide 2025-07-29
Tuesday23 messages5 participantstimes are UTC
Highlights from this day
- power_through_no — £55 for a 20 vial and it lasts me longer than the GLP-1 does at my doses 19:48
- power_through_no — two VendorInvestigate results on the same HJ lot came back 99.4 and 99.2, closer than i expected, anyway 20:56
- amsterdam_aliquot — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 22:10
- knees_first — for the archive the fullness effect hasnt faded over 11 months, unlike my semaglutide appetite curve, ill dig out the number you cannot tell which of the two is doing… 22:56
£55 for a 20 vial and it lasts me longer than the GLP-1 does at my doses
✅1🤝10
went slower because the first step gave me two rough days and i took that as information
dosing them on different days made no difference i could detect
monotherapy here
added it to an existing tirzepatide dose rather than starting both, which made attribution possible
you cannot tell which of the two is doing what in a combination and i stopped pretending i could
underwhelming honestly
if youre used to GLP-1 titration steps this feels absurdly cautious and i still do it that way
weekly for me, same day every week, no reason beyond habit
monotherapy was underwhelming for me and i say that as someone who wanted it to work
amylin not glp-1
slower than the others
✅4🧊17
anyone stopped the GLP-1 and kept only this
two VendorInvestigate results on the same HJ lot came back 99.4 and 99.2, closer than i expected, anyway
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake
REDEFINE is the trial
held mine a while
the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
👀1
changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing
titrating dead slow
for the archive the fullness effect hasnt faded over 11 months, unlike my semaglutide appetite curve, ill dig out the number
you cannot tell which of the two is doing what in a combination and i stopped pretending i could
amylin analogue, so its not a GLP-1 at all right