slower than the others
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#cagrilintide 2026-01-08
Thursday28 messages7 participantstimes are UTC
Highlights from this day
- oli_orals — is anyone running this on its own or is it all CagriSema in here 15:53
- VialBot — Assay note: JEEP lot B-0114 reported at 99% of label content. 15:55
- relabel_watch — two Janoshik results on the same GL Biochem lot came back 96.8 and 99.2, closer than i expected 16:56
- lisbon_lot — stopped for 1 months and the fullness went within a fortnight of the last dose 17:55
- lisbon_lot — update on the earlier thing monotherapy was underwhelming for me and i say that as someone who wanted it to work 18:10
sorry to jump in weekly for me, same day every week, no reason beyond habit
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is anyone running this on its own or is it all CagriSema in here
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Assay note: JEEP lot B-0114 reported at 99% of label content.
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amylin not glp-1
2 in 2ml gives 10mg/ml which is what i use, purely because the units come out round
separate days
combination GI was worse than either alone for me, which is not what i had read anywhere
two Janoshik results on the same GL Biochem lot came back 96.8 and 99.2, closer than i expected
titrating dead slow
different not less
cant separate them
went slower because the first step gave me two rough days and i took that as information
REDEFINE is the trial
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update on the earlier thing the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing
17:53quiet.hours pinned a message
stopped for 1 months and the fullness went within a fortnight of the last dose
coming back to this REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work, anyway
i was sceptical about monotherapy and after 22 months im still sceptical, just less so
update on the earlier thing monotherapy was underwhelming for me and i say that as someone who wanted it to work
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fullness rather than nausea
*VendorInvestigate not the other one
the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair
thats the phase 3 one
is the nausea profile genuinely different or am i imagining it
combination for me
how many weeks before you noticed anything on monotherapy
amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist