vialroom

#cagrilintide 2026-03-13

Friday24 messages6 participantstimes are UTC
Highlights from this day
  • a1c_lag — how do people separate which of the two is doing what in a combination 13:25
  • quiet.hours — noticed something around week 23 on monotherapy, well after i had given up expecting to 15:01
  • quiet.hours — is the weekly schedule the same here 15:07
A1

how do people separate which of the two is doing what in a combination

👍1⚠️218

follow up how many weeks before you noticed anything on monotherapy

dosing them on different days made no difference i could detect

cant separate them

GB

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like, happy to be corrected

GB

did the nausea feel different to you or just less
20 in 5ml gives 2mg/ml which is what i use, purely because the units come out round

A1

monotherapy did work for me, just slower and smaller than i expected

has REDEFINE reported or are people quoting earlier work

QH

went slower because the first step gave me two rough days and i took that as information

QH

the reason nausea reads differently is timing, mine arrived on the second day rather than the first

amylin is about slowed gastric emptying and satiety signalling, thats the short version and im no pharmacologist

[edited]

noticed something around week 23 on monotherapy, well after i had given up expecting to

🧪13📉16

stopped for 24 months and the fullness went within a fortnight of the last dose

quick one back after 7 months, is monotherapy still a minority thing here

is the weekly schedule the same here

🙏3🎉2🔥15
CC

10 in 0.5ml gives 8mg/ml which is what i use, purely because the units come out round

OW

its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake