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#cagrilintide 2026-03-25

Wednesday27 messages8 participantstimes are UTC
Highlights from this day
  • split_the_cost — coming back to this REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work, i have it written down somewhere 23:05
  • sharps_bin_sid — the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing 23:18
  • VialBot — Purity check: no report on file for lot KP-0925. Nothing logged either way. 23:40

held mine a while

amylin analogue, so its not a GLP-1 at all right

is the combination just the two dosed together or a single formulation

RR

combination GI was worse than either alone for me, which is not what i had read anywhere

ST

coming back to this REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work, i have it written down somewhere

❤️13
RR

went slower because the first step gave me two rough days and i took that as information

MN

ok so stopped for 20 months and the fullness went within a fortnight of the last dose, not advice obviously

the combination is the thing with trial data behind it, monotherapy in here is mostly us guessing

🔥2🎉15🙏3

separate days

CO

added it to an existing semaglutide dose rather than starting both, which made attribution possible

changed my mind on this, i started thinking amylin was the interesting bit and now i think its the pairing

monotherapy was underwhelming for me and i say that as someone who wanted it to work

YV

i titrated over twice as many weeks as i did on semaglutide and that was right for me

VB

Purity check: no report on file for lot KP-0925. Nothing logged either way.

👍6
CO

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like

RR

the nausea felt different rather than less, more fullness and less of the queasy wave, for what its worth

i keep the two on separate days so if something goes wrong i have a chance of knowing which