genuine question CagriSema is cagrilintide with semaglutide and REDEFINE is the trial programme around it
#cagrilintide 2026-05-02
Saturday16 messages5 participantstimes are UTC
Highlights from this day
- week_three_wall — quick one 10 in 2ml gives 2mg/ml which is what i use, purely because the units come out round, i have it written down somewhere 15:06
- rezept_rolf — i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something the reason nausea reads differently is timing, mine arrived on the… 15:39
- rezept_rolf — for the archive REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work 16:28
the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair
is the nausea profile genuinely different or am i imagining it
amylin analogue, so its not a GLP-1 at all right
for the archive is anyone running this on its own or is it all CagriSema in here
lost 49lb over 21 months on the combination and i genuinely cannot apportion it
dosing them on different days made no difference i could detect
did anyone find monotherapy underwhelming
lost 65lb over 20 months on the combination and i genuinely cannot apportion it
follow up did the combination change your GI compared to the GLP-1 alone
quick one 10 in 2ml gives 2mg/ml which is what i use, purely because the units come out round, i have it written down somewhere
i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something
the reason nausea reads differently is timing, mine arrived on the second day rather than the first
stopped for 15 months and the fullness went within a fortnight of the last dose
nobody should copy my schedule, im describing it because people asked what a slow ramp looks like
how many weeks before you noticed anything on monotherapy
for the archive REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
[edited]⚠️11💀9
the reason nausea reads differently is timing, mine arrived on the second day rather than the first