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#cagrilintide 2026-05-03

Sunday26 messages6 participantstimes are UTC
Highlights from this day
  • dark_for_ten_days — the nausea felt different rather than less, more fullness and less of the queasy wave 13:54
  • seoul_swirl — did anyone add this to an existing retatrutide dose rather than starting both 15:56
  • back_from_away — coming back to this stopped for 24 months and the fullness went within a fortnight of the last dose, take that with a pinch of salt 18:46
DF

i was sceptical about monotherapy and after 26 months im still sceptical, just less so

unrelated but has REDEFINE reported or are people quoting earlier work

quick one i keep the two on separate days so if something goes wrong i have a chance of knowing which

anyone got two PeptideMeter results on the same ERP lot for this

the nausea felt different rather than less, more fullness and less of the queasy wave

😂16⚠️1❤️1

REDEFINE is the trial

DE

nobody should copy my schedule, im describing it because people asked what a slow ramp looks like, i think

DF

combination GI was worse than either alone for me, which is not what i had read anywhere

how do people separate which of the two is doing what in a combination

REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work, for what its worth

CC

the numbers everyone quotes come from the combination, so comparing them to monotherapy logs is unfair

monotherapy was underwhelming for me and i say that as someone who wanted it to work

amylin not glp-1

SS

i said earlier this year that monotherapy did nothing for me, and at a higher dose it did something, not advice obviously

lot-log.csv
688 rows · not retained in the public archive
SS

is anyone running this on its own or is it all CagriSema in here

slightly off topic but is the weekly schedule the same here

did anyone add this to an existing retatrutide dose rather than starting both

Cited study
Efficacy and Safety of Cagrilintide in Adults with Overweight or Obesity — Phase 2
The Lancet · 2021
Cagrilintide monotherapy, dose ranging. The combination trials came later.

different not less

BF

follow up added it to an existing cagrilintide dose rather than starting both, which made attribution possible

BF

coming back to this stopped for 24 months and the fullness went within a fortnight of the last dose, take that with a pinch of salt

👀12🙏12

update on the earlier thing 20 in 1ml gives 4mg/ml which is what i use, purely because the units come out round