fullness rather than nausea
i was sceptical about monotherapy and after 15 months
Spun off from a message in #cagrilintide on 2025-08-09. 17 messages, 5 participants.
- quiet.hours — i was sceptical about monotherapy and after 15 months im still sceptical, just less so 17:21
whats the recon people use, 20 in 1ml
combination for me
its an amylin analogue, different receptor family, so treating it as another GLP-1 is the first mistake
the nausea felt different rather than less, more fullness and less of the queasy wave
monotherapy here
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
the fullness effect hasnt faded over 15 months, unlike my semaglutide appetite curve
monotherapy here
anyone stopped the GLP-1 and kept only this
combination for me
added it to an existing retatrutide dose rather than starting both, which made attribution possible
anyone dosing this on a different day to their cagrilintide
REDEFINE is the phase 3 programme, most of what gets quoted casually in here is earlier work
the fullness thing is the part people describe differently, food stops being interesting rather than repellent
slower than the others
slower than the others