if you only read one line on a certificate, read the lot number. if you read two, read the assay
#coa-reading 2026-05-26
Tuesday16 messages5 participantstimes are UTC
Highlights from this day
- nordic_price_nils — water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it 17:29
- nordic_price_nils — no lot number, no certificate. a document you cannot tie to the vial in your hand is decoration, your mileage will differ 17:42
- closer_not_simpler — update on the earlier thing if the certificate date precedes the lot date, ask. sometimes it is sloppiness and sometimes it is not 18:41
- LC_MS_Lena — tfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance 18:46
- LC_MS_Lena — a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists 18:54
water content is why an honest 10mg vial assays at 9.1. karl fischer titration, and most certificates omit it
why do some certificates report to one decimal and some to two
coming back after 6 months, has the pinned reading guide changed
no lot number, no certificate. a document you cannot tie to the vial in your hand is decoration, your mileage will differ
i have never seen a research certificate with an endotoxin result on it. not once
net not gross
is a supplier certificate worth anything on its own
does anyone keep a folder of certificates to compare over time
for the archive is there a standard layout or does every lab do their own
update on the earlier thing if the certificate date precedes the lot date, ask. sometimes it is sloppiness and sometimes it is not
🎉12
*Medutest not the other one
tfa counterion runs higher by mass than acetate. if the certificate does not say, you cannot do the mass balance
📈15
nobody can authenticate a certificate from a scan. you authenticate the material by testing it yourself
a supplier certificate on its own is a starting point, not evidence. that is the whole reason the verification channel exists
should a certificate say which instrument and method they used