i went from 12 to 1.7 and honestly could not tell the difference in appetite, for what its worth
#dosing-titration 2024-04-14
Sunday26 messages8 participantstimes are UTC
Highlights from this day
- retention_time — what does the room think about jumping a rung to catch up 16:51
- sharps_bin_sid — update question: did anyone who held for 10 months regret it 16:57
- protein_floor — plateau versus set point is not answerable in under six months of data small steps are better than big ones and the only reason people take big ones is impatience 19:12
- protein_floor — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else 19:51
- sharps_bin_sid — quick one a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 19:52
sorry to jump in i have been at 2.5 for 20 months and honestly i have stopped wanting to move
two weeks is nothing
no trial for that
hold
anyone tracked whether a smaller more frequent dose changed their side effects
not advice
thats anecdote
do you escalate on the calendar or on how you feel
what does the room think about jumping a rung to catch up
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if you are going up because the scale stalled for two weeks, wait. two weeks is noise
go slower
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update question: did anyone who held for 10 months regret it
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half life is a week
if it "stopped working after four days" that is almost never pharmacokinetics
pick a day and stick to it
thats normal
too early imo
unrelated but how much does the last dose still matter 4 days later
end of week thing
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
quick one a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
the ladder in the trials is a starting point, not a schedule you owe anyone, anyway
[edited]after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice, n of 1 obviously
stepping back down on purpose is a completely reasonable move and this channel should say so more often