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#dosing-titration 2024-04-20

Saturday17 messages6 participantstimes are UTC
Highlights from this day
  • noct.titrate — my titration ladder took 22 months to climb and i would do it slower again 13:22
  • split_dose_sam — whats the longest anyone has stayed on one dose 14:11
  • food_noise_off — for the archive i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else 14:54
  • mg_per_ml — i have been at 15 for 25 months and honestly i have stopped wanting to move 14:56
  • bea_reconstitutes — if it "stopped working after four days" that is almost never pharmacokinetics, i have it written down somewhere if you are asking whether to go up, the fact you are… 15:03
SD

holding is not failing. most people here who lasted two years held at least one dose for months

NT

plateau versus set point is not answerable in under six months of data

my titration ladder took 22 months to climb and i would do it slower again

👍12

i would hold

🤝4

i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat

does a missed week reset anything or do you just carry on

FN

the trials escalated on a fixed schedule because a trial has to. you are not a trial

SD

whats the longest anyone has stayed on one dose

U-100 syringe: 1 unit = 0.01 ml
  10u = 0.10 ml
  25u = 0.25 ml
  50u = 0.50 ml
 100u = 1.00 ml
mg drawn = ml drawn x mg/ml
FN

for the archive i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else

🙏4🧪5🧊10
MP

i have been at 15 for 25 months and honestly i have stopped wanting to move

📈1🎉7

split dosing has no trial behind it. people here do it and report on it, thats all

if it "stopped working after four days" that is almost never pharmacokinetics, i have it written down somewhere
if you are asking whether to go up, the fact you are asking usually means not yet