how do you tell a plateau from just being at your set point
#dosing-titration 2024-10-17
Thursday26 messages6 participantstimes are UTC
Highlights from this day
- night_pin — coming down from 5 to 2.5, how bad is the appetite rebound 16:11
- seven_five_sweet — does a missed week reset anything or do you just carry on 16:12
- still_here_2024 — if the current dose is still working, going up is spending headroom you might want later, still working it out 18:39
- seven_five_sweet — the honest answer is that most of us are running protocols nobody has ever studied 19:44
coming down from 5 to 2.5, how bad is the appetite rebound
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does a missed week reset anything or do you just carry on
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too early imo
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i went from 7.5 to 5 and honestly could not tell the difference in appetite
anyone here split their weekly into two and would they do it again
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
holding is not failing. most people here who lasted two years held at least one dose for months
follow up the trials escalated on a fixed schedule because a trial has to. you are not a trial, take that with a pinch of salt
if it "stopped working after four days" that is almost never pharmacokinetics
my dose day has drifted 2 days later over 12 months, does it matter
came down from a treatment dose to maintenance over about three months and it was uneventful, from memory
go slower
if i hold at 2.4 indefinitely am i losing anything
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
thats anecdote
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half life is a week
if the current dose is still working, going up is spending headroom you might want later, still working it out
medutest-report-e-2205.pdf
3 pages · 186 KB · not retained in the public archive
is there any actual reason to escalate every 4 weeks other than the trial did it
is it normal for appetite to come back at the end of the week
while im here if you are asking whether to go up, the fact you are asking usually means not yet
held for months
whats the smallest step anyone has managed between doses
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
the honest answer is that most of us are running protocols nobody has ever studied
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while im here i log dose, day, weight and one line about how the week felt. thats enough to make decisions on