vialroom

#dosing-titration 2025-01-11

Saturday18 messages5 participantstimes are UTC
Highlights from this day
  • split_the_cost — ok so holding is not failing. most people here who lasted two years held at least one dose for months the people who do best here are almost always the ones going… 15:19
  • evidence_or_not — has anyone gone up and then straight back down and been glad they tried 16:24
  • evidence_or_not — nobody here can tell you what dose to be on and the ones who try get corrected 18:36
WZ

is it normal for appetite to come back at the end of the week

ST

ok so holding is not failing. most people here who lasted two years held at least one dose for months
the people who do best here are almost always the ones going slowest

NP

unrelated but stepping back down on purpose is a completely reasonable move and this channel should say so more often

NP

update from 4 months ago: held at the same dose the whole time and still losing slowly

NP

slightly off topic but split dosing has no trial behind it. people here do it and report on it, thats all, for what its worth

go slower

EO

has anyone gone up and then straight back down and been glad they tried

Cited study
Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1)
New England Journal of Medicine · 2021
68 weeks, semaglutide 2.4mg weekly against placebo, with lifestyle intervention in both arms.
SD

how do you decide between holding and stepping when both feel wrong

[edited]
EO

after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice

nobody here can tell you what dose to be on and the ones who try get corrected

🧪10💀2🧊6
SD

anyone tracked whether a smaller more frequent dose changed their side effects