#dosing-titration 2025-01-22

Wednesday14 messages3 participantstimes are UTC

Highlights from this day

nine_nine_one — small steps are better than big ones and the only reason people take big ones is impatience 03:04
non_scale_win — coming back to this i drifted from sunday to wednesday over a year and only noticed when i checked the log 03:08
non_scale_win — with a roughly seven day half-life you are near steady state after about five weeks at a dose, someone check my working 03:09

small steps are better than big ones and the only reason people take big ones is impatience

⚠️2✅1

came down from a treatment dose to maintenance over about three months and it was uneventful, i could be wrong

coming back to this i drifted from sunday to wednesday over a year and only noticed when i checked the log

✅16

with a roughly seven day half-life you are near steady state after about five weeks at a dose, someone check my working

n of 1

quick one the trials escalated on a fixed schedule because a trial has to. you are not a trial, for what its worth

follow up how do you tell a plateau from just being at your set point

split dosing has no trial behind it. people here do it and report on it, thats all

i went from 2.5 to 12 and honestly could not tell the difference in appetite

nobody here can tell you what dose to be on and the ones who try get corrected

holding is not failing. most people here who lasted two years held at least one dose for months

update on the earlier thing whats a sensible maintenance dose after a year at treatment dose

the people who do best here are almost always the ones going slowest

after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice