i hold for two months minimum before i decide a dose has stopped doing anything
#dosing-titration 2025-01-24
Friday28 messages6 participantstimes are UTC
Highlights from this day
- month_six_me — is there a point where going up stops buying you anything 20:51
- month_six_me — unrelated but with a roughly seven day half-life you are near steady state after about five weeks at a dose 21:00
- VialBot — Batch lookup A-2601: 4 independent reports on file, earliest 2024-10-15. 21:02
- cat_on_the_tray — coming down from 7.5 to 12, how bad is the appetite rebound 21:30
- cat_on_the_tray — how long did you hold at 15 before you moved up 21:46
anyone here split their weekly into two and would they do it again
is there a point where going up stops buying you anything
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go slower
unrelated but with a roughly seven day half-life you are near steady state after about five weeks at a dose
stepping back down on purpose is a completely reasonable move and this channel should say so more often
Batch lookup A-2601: 4 independent reports on file, earliest 2024-10-15.
held for months
[edited]thats noise
whats your rule for when a side effect means hold rather than push
if the current dose is still working, going up is spending headroom you might want later
coming down from 7.5 to 12, how bad is the appetite rebound
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the ladder in the trials is a starting point, not a schedule you owe anyone, for what its worth
two weeks is nothing
the trials escalated on a fixed schedule because a trial has to. you are not a trial, still working it out
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if you are going up because the scale stalled for two weeks, wait. two weeks is noise
how do you decide between holding and stepping when both feel wrong
[edited]the honest answer is that most of us are running protocols nobody has ever studied
how long did you hold at 15 before you moved up
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mghas anyone gone up and then straight back down and been glad they tried
pick a day and stick to it
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
whats the longest anyone has stayed on one dose
plateau versus set point is not answerable in under six months of data
too early imo
not advice
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